Racial ranking of genetically predisposed to anxiety(S allele)

sense of anxiety

What is the S allele associated with anxiety?

 There is a substance called serotonin, which is a liaison between nerves. This has the property that the anxiety decreases if it increases, and the uneasiness increases if it decreases. And, the device which brings the serotonin released from the nerve again into the nerve and reduces the amount of serotonin between the nerves is called a serotonin transporter.

 We know that there are individual differences in the blueprints of this serotonin transporter, and that the number of repetitions of a particular genetic sequence is different. The genes with little repetition are S (Short) and many genes are two- and L (Long).

 The composition of serotonin transporters produced in S and L is very different, and it has been found that those with the S gene are more likely to feel anxious, and those with the L gene are less likely to feel uneasy. In addition, since these are held in conflict, there are three types of people: L/L type, L/S type, and S/S type.

 If you line up with the ease of feeling uneasy,

Anxiety S/S Type > L/S Type > L/L Type 

It comes to.

 Well, what are the many gene types of Japanese people, and what differences are there compared with the peoples of the world?

Ethnic rankings that are genetically prone to anxiety

 When the experiment which examined the ratio of the ally gene of L and S examined worldwide is aggregated, the result like the graph below is shown.

 If you look at the graph above, you can see that the proportion of Japanese S gene is high in the data examined. It is well understood that the Japanese are genetically the world’s top class and easy to feel uneasy.

 It is not special that Japanese people are easy to feel uneasy, but it is extremely natural from the mechanism of nerves.

The ranking shows that East Asian races tend to be more prone to anxiety. Conversely, the African continent tends to be optimistic. In today’s world, where we often come into contact with people from all over the world for business, it may help us to understand each other more quickly if we keep such data in mind when interacting with each other.

Reference

  1. Esau, L., Kaur, M., Adonis, L. & Arieff, Z. The 5-HTTLPR polymorphism in South African healthy populations: a global comparison. J Neural Transm 115, 755–760 (2008).

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